Cadiss® Surgical System
Product Description
CADISS® (Chemically Assisted Dissection System) is an advanced surgical system designed to simplify tissue dissection by selectively weakening fibrotic adhesions. Through the targeted topical application of Mesna, CADISS® enables fast, controlled separation of tissues without cutting, helping preserve surrounding structures such as nerves and veins. Clinically proven and CE Class III certified, CADISS® improves procedural efficiency while reducing surgical trauma and postoperative complications.
The Aim
CADISS® facilitates the tissue dissection by weakening adhesions between tissues.
The System
CADISS® enables topical application of the drug at the surgery site. Within seconds, the adhesion is weakened and separation is performed with the same instrument.
The Benefits
- Reduce surgery side-effects
- Reduce surgery side-effects
- Reduce relapses
- Facilitates procedures
Proof of Principle
Safety
Absence of toxicity demonstrated, no side effects/no risks, registered as CE Class III, tested in many investigational clinical trials (13 published studies, 900 patients).
Chemically assisted dissection
Disulfide bonds, very frequent in fibrosis, are in large part responsible for the strength of adherence between tissues. Topical application of the drug Mesna breaks selectively these disulfide bonds, resulting in weakened adhesions. This CADISS® system was invented by a team of the University of Parma under the direction of Professor Carlo Zini.
Disulfide bonds, very frequent in fibrosis, are in large part responsible for the strength of adherence between tissues. Topical application of the drug Mesna breaks selectively these disulfide bonds, resulting in weakened adhesions. This CADISS® system was invented by a team of the University of Parma under the direction of Professor Carlo Zini.
Selective mechanical dissection without cutting
CADISS® enables a selective dissection WITHOUT cutting by using the Mesna dispended through its surgical instruments. Therefore, surrounding organs are well preserved (nerves and veins).
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